Denis Mirlesse practices hypnotherapy and  acupuncture in London. He has worked for a number of years with substance misuse organizations. He received his initial training in hypnosis in 1985 while conducting research and lecturing at the University of Pennsylvania in Philadelphia, and trained further with Michael Yapko and Jeffrey Zeig.

Denis is affiliated with the International Society of Hypnosis, the British Psychological Society, the Acupuncture Society, and the Royal Society of Medicine.